Brachyspira species and gastroenteritis in humans.

Isolation and characterization of Brachyspira species based on biochemical scheme and 16S rDNA partial sequencing

Avian intestinal spirochetosis (AIS) is a disease of birdscharacterized by a marked colonization of the cecum and/or rectumwith anaerobic intestinal bacteria of the genus Brachyspira. Thepurpose of the study was to determine the occurrence of Brachyspiraspp from avian sources in Iran and to characterize selected isolates bybiochemical and molecular methods. Out of 165 fecal samples obtained fro...

Gastrointestinal infection with Brachyspira spp in a filly with chronic diarrhea: a case report

An eleven month old filly was referred to the Research and Teaching Hospital of the Faculty of Veterinary Medicine at the University of Tehran. The animal presented a three-week history of diarrhea and previous treatments had failed to effect a recovery. Based on the history, clinical findings and results of laboratory investigations, it was assumed that a gastrointestinal disorder was affectin...

Development of a Real-Time PCR for Identification of Brachyspira Species in Human Colonic Biopsies

BACKGROUND Brachyspira species are fastidious anaerobic microorganisms, that infect the colon of various animals. The genus contains both important pathogens of livestock as well as commensals. Two species are known to infect humans: B. aalborgi and B. pilosicoli. There is some evidence suggesting that the veterinary pathogenic B. pilosicoli is a potential zoonotic agent, however, since diagnos...

Epidemiological aspects and improved differential diagnostics of porcine Brachyspira pilosicoli

Presence of Brachyspira aalborgi and B. pilosicoli in feces of patients with diarrhea.

Anaerobic intestinal spirochetes of the genus Brachyspira are important enteric pathogens in animals, but they have not been extensively studied in humans. The presence of a layer of spirochetes attached by one cell end to the colorectal epithelium is known as intestinal spirochetosis (IS) (4). The clinical significance of this colonization is uncertain, but it has been linked to chronic diarrh...